Cargando…

MERS-CoV and SARS-CoV-2 replication can be inhibited by targeting the interaction between the viral spike protein and the nucleocapsid protein

Background: The molecular interactions between viral proteins form the basis of virus production and can be used to develop strategies against virus infection. The interactions of the envelope proteins and the viral RNA-binding nucleocapsid (N) protein are essential for the assembly of coronaviruses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Byoung Kwon, Kim, Jinsoo, Park, Sangkyu, Kim, Dongbum, Kim, Minyoung, Baek, Kyeongbin, Bae, Joon-Yong, Park, Man-Seong, Kim, Won-Keun, Lee, Younghee, Kwon, Hyung-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914343/ https://www.ncbi.nlm.nih.gov/pubmed/33664866 http://dx.doi.org/10.7150/thno.55647

Ejemplares similares

Abiraterone Acetate Attenuates SARS-CoV-2 Replication by Interfering with the Structural Nucleocapsid Protein
por: Kim, Jinsoo, et al.
Publicado: (2022)

Analysis of spike protein variants evolved in a novel in vivo long-term replication model for SARS-CoV-2
por: Kim, Dongbum, et al.
Publicado: (2023)

Targeting the Interaction Between Spike Protein and Nucleocapsid Protein for Suppression and Detection of Human Coronavirus OC43
por: Kim, Jinsoo, et al.
Publicado: (2022)

Production of SARS-CoV-2 N Protein-Specific Monoclonal Antibody and Its Application in an ELISA-Based Detection System and Targeting the Interaction Between the Spike C-Terminal Domain and N Protein
por: Kim, Dongbum, et al.
Publicado: (2021)

Production of a Monoclonal Antibody to the Nucleocapsid Protein of SARS-CoV-2 and Its Application to ELISA-Based Detection Methods with Broad Specificity by Combined Use of Detector Antibodies
por: Kim, Jinsoo, et al.
Publicado: (2022)

Differential effect of SARS-CoV-2 infection on stress granule formation in Vero and Calu-3 cells
por: Kim, Dongbum, et al.
Publicado: (2022)

MUC1-C influences cell survival in lung adenocarcinoma Calu-3 cells after SARS-CoV-2 infection
por: Kim, Dongbum, et al.
Publicado: (2021)

Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection
por: Park, Byoung Kwon, et al.
Publicado: (2021)

Apoptosis Enhances the Replication of Human Coronavirus OC43
por: Maharjan, Sony, et al.
Publicado: (2021)

Production of a Monoclonal Antibody Targeting the M Protein of MERS-CoV for Detection of MERS-CoV Using a Synthetic Peptide Epitope Formulated with a CpG–DNA–Liposome Complex
por: Park, Byoung Kwon, et al.
Publicado: (2018)

Generation and characterization of a monoclonal antibody against MERS-CoV targeting the spike protein using a synthetic peptide epitope-CpG-DNA-liposome complex
por: Park, Byoung Kwon, et al.
Publicado: (2019)

Safe, high-throughput screening of natural compounds of MERS-CoV entry inhibitors using a pseudovirus expressing MERS-CoV spike protein
por: Kim, Ji Yeun, et al.
Publicado: (2018)

Antibody detection of SARS-CoV spike and nucleocapsid protein
por: Chang, Mau-Sun, et al.
Publicado: (2004)

Variations in Spike Glycoprotein Gene of MERS-CoV, South Korea, 2015
por: Kim, Dae-Won, et al.
Publicado: (2016)

MERS-CoV spike protein: Targets for vaccines and therapeutics
por: Wang, Qihui, et al.
Publicado: (2016)

MERS-CoV spike nanoparticles protect mice from MERS-CoV infection
por: Coleman, Christopher M., et al.
Publicado: (2017)

A chimeric MERS-CoV virus-like particle vaccine protects mice against MERS-CoV challenge
por: Park, Jung-Eun, et al.
Publicado: (2022)

Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation
por: Youn, Young-Jin, et al.
Publicado: (2021)

Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy
por: D’Arco, Annalisa, et al.
Publicado: (2023)

Identification of Conserved Epitopes in SARS-CoV-2 Spike and Nucleocapsid Protein
por: Forcelloni, Sergio, et al.
Publicado: (2021)

Cross-Protection against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and Protein
por: Choi, Jung-ah, et al.
Publicado: (2020)

Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2
por: Hatmal, Ma’mon M., et al.
Publicado: (2020)

Discovery of New Potent anti-MERS CoV Fusion Inhibitors
por: Kandeel, Mahmoud, et al.
Publicado: (2021)

Immunogenicity of Candidate MERS-CoV DNA Vaccines Based on the Spike Protein
por: Al-amri, Sawsan S., et al.
Publicado: (2017)

Genetic diversity of MERS-CoV spike protein gene in Saudi Arabia
por: Sohrab, Sayed S., et al.
Publicado: (2020)

Analysis of proteins that interact with nucleocapsid protein of SARS-CoV using 15-mer phage-displayed library
por: Liu, ZhengXue, et al.
Publicado: (2007)

Effect of Previous COVID-19 Vaccination on Humoral Immunity 3 Months after SARS-CoV-2 Omicron Infection and Booster Effect of a Fourth COVID-19 Vaccination 2 Months after SARS-CoV-2 Omicron Infection
por: Kim, Jinsoo, et al.
Publicado: (2022)

Electrostatic features for nucleocapsid proteins of SARS-CoV and SARS-CoV-2
por: Guo, Wenhan, et al.
Publicado: (2021)

Measuring DNA folding by the SARS-CoV-2 nucleocapsid protein
por: Kim, Jake J., et al.
Publicado: (2023)

Substitutions in Spike and Nucleocapsid proteins of SARS-CoV-2 circulating in South America
por: Franco-Muñoz, Carlos, et al.
Publicado: (2020)

Computational studies of the dynamics of SARS-CoV-2 spike, membrane, and nucleocapsid proteins
por: Dutta, Mandira, et al.
Publicado: (2022)

Inclusion of MERS‐spike protein ELISA in algorithm to determine serologic evidence of MERS‐CoV infection
por: Trivedi, Suvang, et al.
Publicado: (2017)

The Epitope Study on the SARS-CoV Nucleocapsid Protein
por: Li, Shuting, et al.
Publicado: (2003)

MERS-CoV
por: Müller, Marcel A
Publicado: (2014)

Human post‐infection serological response to the spike and nucleocapsid proteins of SARS‐CoV‐2
por: Xiao, Cheng, et al.
Publicado: (2020)

Susceptibility to SARS-CoV-2 and MERS-CoV in Beagle Dogs
por: Lyoo, Kwang-Soo, et al.
Publicado: (2023)

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors
por: Park, Young-Jun, et al.
Publicado: (2019)

Inability of rat DPP4 to allow MERS-CoV infection revealed by using a VSV pseudotype bearing truncated MERS-CoV spike protein
por: Fukuma, Aiko, et al.
Publicado: (2015)

SARS-CoV-2 Spike Protein Vaccine-Induced Immune Imprinting Reduces Nucleocapsid Protein Antibody Response in SARS-CoV-2 Infection
por: Delgado, Juan F., et al.
Publicado: (2022)

Comparison of vaccination efficacy using live or ultraviolet-inactivated influenza viruses introduced by different routes in a mouse model
por: Baek, Kyeongbin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bgbm16elf55omneilrdo37ksa5