Sunitinib-induced cardiac hypertrophy and the endothelin axis

Anti-angiogenics drugs in clinical use for cancer treatment induce cardiotoxic side effects. The endothelin axis is involved in hypertension and cardiac remodelling, and addition of an endothelin receptor antagonist to the anti-angiogenic sunitinib was shown to reduce cardiotoxicity of sunitinib in...

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Detalles Bibliográficos
Autores principales: Sourdon, Joevin, Facchin, Caterina, Certain, Anaïs, Viel, Thomas, Robin, Blaise, Lager, Franck, Marchiol, Carmen, Balvay, Daniel, Yoganathan, Thulaciga, Favier, Judith, Tharaux, Pierre-Louis, Dhaun, Neeraj, Renault, Gilles, Tavitian, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914356/
https://www.ncbi.nlm.nih.gov/pubmed/33664864
http://dx.doi.org/10.7150/thno.49837

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