Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma

Background: Methyltransferase-like 14 (METTL14) participates in tumorigenesis in several malignancies, but how METTL14 mediates the metastasis of renal cell carcinoma (RCC) has never been reported. Methods: Western blotting, quantitative real-time PCR, and immunohistochemistry were used to determine...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chuanjie, Chen, Li, Liu, Yihan, Huang, Jingyi, Liu, Ao, Xu, Yang, Shen, Yan, He, Hongchao, Xu, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914369/
https://www.ncbi.nlm.nih.gov/pubmed/33664855
http://dx.doi.org/10.7150/thno.55424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914369/
https://www.ncbi.nlm.nih.gov/pubmed/33664855
http://dx.doi.org/10.7150/thno.55424

Ejemplares similares