Preliminary Structural Elucidation of β-(1,3)-glucan Synthase from Candida glabrata Using Cryo-Electron Tomography

Echinocandin drugs have become a front-line therapy against Candida spp. infections due to the increased incidence of infections by species with elevated azole resistance, such as Candida glabrata. Echinocandins target the fungal-specific enzyme ß-(1,3)-glucan synthase (GS), which is located in the...

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Autores principales: Jiménez-Ortigosa, Cristina, Jiang, Jennifer, Chen, Muyuan, Kuang, Xuyuan, Healey, Kelley R., Castellano, Paul, Boparai, Nikpreet, Ludtke, Steven J., Perlin, David S., Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914498/
https://www.ncbi.nlm.nih.gov/pubmed/33562124
http://dx.doi.org/10.3390/jof7020120

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