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Relationship between Delta Rhythm, Seizure Occurrence and Allopregnanolone Hippocampal Levels in Epileptic Rats Exposed to the Rebound Effect

Abrupt withdrawal from antiepileptic drugs is followed by increased occurrence of epileptic seizures, a phenomenon known as the “rebound effect”. By stopping treatment with levetiracetam (LEV 300 mg/kg/day, n = 15; vs. saline, n = 15), we investigated the rebound effect in adult male Sprague-Dawley...

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Detalles Bibliográficos
Autores principales: Costa, Anna-Maria, Lucchi, Chiara, Malkoç, Asiye, Rustichelli, Cecilia, Biagini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914513/
https://www.ncbi.nlm.nih.gov/pubmed/33561937
http://dx.doi.org/10.3390/ph14020127

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