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Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire
Little research has examined the effects of high concentration, medium-duration smoke exposure on cardiovascular health. We investigated whether six weeks of exposure to smoke from the 2014 Hazelwood coal mine fire in Victoria (Australia), was associated with long-term clinical or subclinical cardio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914645/ https://www.ncbi.nlm.nih.gov/pubmed/33567509 http://dx.doi.org/10.3390/ijerph18041587 |
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author | Betts, Juliana Dewar, Elizabeth M. Stub, Dion Gao, Caroline X. Brown, David W. Ikin, Jillian F. Zeleke, Berihun M. Biswas, Sinjini Abramson, Michael J. Liew, Danny |
author_facet | Betts, Juliana Dewar, Elizabeth M. Stub, Dion Gao, Caroline X. Brown, David W. Ikin, Jillian F. Zeleke, Berihun M. Biswas, Sinjini Abramson, Michael J. Liew, Danny |
author_sort | Betts, Juliana |
collection | PubMed |
description | Little research has examined the effects of high concentration, medium-duration smoke exposure on cardiovascular health. We investigated whether six weeks of exposure to smoke from the 2014 Hazelwood coal mine fire in Victoria (Australia), was associated with long-term clinical or subclinical cardiovascular disease approximately four years later, in adult residents of the towns of Morwell (exposed, n = 336) and Sale (unexposed, n = 162). The primary outcome was serum high sensitivity (hs) C-reactive protein (CRP). Blood pressure, electrocardiogram, flow mediated dilatation and serum levels of hs-troponin, N-terminal pro B-type natriuretic peptide and lipids were secondary outcomes. There was no significant difference in weighted median hsCRP levels between exposed and unexposed participants (1.9 mg/L vs. 1.6 mg/L, p = 0.273). Other outcomes were comparable between the groups. hsCRP was associated in a predictable manner with current smoking, obesity and use of lipid-lowering therapy. Four years after a 6-week coal mine fire, this study found no association between smoke exposure and markers of clinical or subclinical cardiovascular disease in exposed adults. |
format | Online Article Text |
id | pubmed-7914645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79146452021-03-01 Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire Betts, Juliana Dewar, Elizabeth M. Stub, Dion Gao, Caroline X. Brown, David W. Ikin, Jillian F. Zeleke, Berihun M. Biswas, Sinjini Abramson, Michael J. Liew, Danny Int J Environ Res Public Health Article Little research has examined the effects of high concentration, medium-duration smoke exposure on cardiovascular health. We investigated whether six weeks of exposure to smoke from the 2014 Hazelwood coal mine fire in Victoria (Australia), was associated with long-term clinical or subclinical cardiovascular disease approximately four years later, in adult residents of the towns of Morwell (exposed, n = 336) and Sale (unexposed, n = 162). The primary outcome was serum high sensitivity (hs) C-reactive protein (CRP). Blood pressure, electrocardiogram, flow mediated dilatation and serum levels of hs-troponin, N-terminal pro B-type natriuretic peptide and lipids were secondary outcomes. There was no significant difference in weighted median hsCRP levels between exposed and unexposed participants (1.9 mg/L vs. 1.6 mg/L, p = 0.273). Other outcomes were comparable between the groups. hsCRP was associated in a predictable manner with current smoking, obesity and use of lipid-lowering therapy. Four years after a 6-week coal mine fire, this study found no association between smoke exposure and markers of clinical or subclinical cardiovascular disease in exposed adults. MDPI 2021-02-08 2021-02 /pmc/articles/PMC7914645/ /pubmed/33567509 http://dx.doi.org/10.3390/ijerph18041587 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Betts, Juliana Dewar, Elizabeth M. Stub, Dion Gao, Caroline X. Brown, David W. Ikin, Jillian F. Zeleke, Berihun M. Biswas, Sinjini Abramson, Michael J. Liew, Danny Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title | Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title_full | Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title_fullStr | Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title_full_unstemmed | Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title_short | Markers of Cardiovascular Disease among Adults Exposed to Smoke from the Hazelwood Coal Mine Fire |
title_sort | markers of cardiovascular disease among adults exposed to smoke from the hazelwood coal mine fire |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914645/ https://www.ncbi.nlm.nih.gov/pubmed/33567509 http://dx.doi.org/10.3390/ijerph18041587 |
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