Cargando…
A Multifocal Pediatric Papillary Thyroid Carcinoma (PTC) Harboring the AGK-BRAF and RET/PTC3 Fusion in a Mutually Exclusive Pattern Reveals Distinct Levels of Genomic Instability and Nuclear Organization
SIMPLE SUMMARY: Genetic alterations, such as RET/PTC and AGK-BRAF fusions, are frequent events in pediatric papillary thyroid carcinoma (PTC). However, their role as prognostic markers in pediatric PTC is still under investigation. In this study, we present a patient harboring three tumor foci with...
Autores principales: | Sisdelli, Luiza, Cordioli, Maria Isabel V., Vaisman, Fernanda, Monte, Osmar, Longui, Carlos A., Cury, Adriano N., Freitas, Monique O., Rangel-Pozzo, Aline, Mai, Sabine, Cerutti, Janete M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914679/ https://www.ncbi.nlm.nih.gov/pubmed/33562578 http://dx.doi.org/10.3390/biology10020125 |
Ejemplares similares
-
AGK‐BRAF gene fusion is a recurrent event in sporadic pediatric thyroid carcinoma
por: Cordioli, Maria Isabel C. V., et al.
Publicado: (2016) -
A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation
por: Ashwini, Basavaraj Rangalakshmi, et al.
Publicado: (2023) -
Assessment of RET/PTC1 and RET/PTC3 rearrangements in fine-needle aspiration biopsy specimens collected from patients with Hashimoto's thyroiditis
por: Cyniak-Magierska, Anna, et al.
Publicado: (2011) -
Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis
por: Su, Xuan, et al.
Publicado: (2016) -
ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells
por: Denning, Karen, et al.
Publicado: (2008)