Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells

Altered lacrimal gland (LG) secretion is a feature of autoimmune dacryoadenitis in Sjögren’s syndrome (SS). Cathepsin S (CTSS) is increased in tears of SS patients, which may contribute to disease. Rab3D and Rab27a/b isoforms are effectors of exocytosis in LG, but Rab27a is poorly studied. To invest...

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Detalles Bibliográficos
Autores principales: Fu, Runzhong, Edman, Maria C., Hamm-Alvarez, Sarah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914720/
https://www.ncbi.nlm.nih.gov/pubmed/33562815
http://dx.doi.org/10.3390/ijms22041630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914720/
https://www.ncbi.nlm.nih.gov/pubmed/33562815
http://dx.doi.org/10.3390/ijms22041630

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