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A Link between Intrahepatic Cholestasis and Genetic Variations in Intracellular Trafficking Regulators

SIMPLE SUMMARY: Cholestasis refers to a medical condition in which the liver is not capable of secreting bile. The consequent accumulation of toxic bile components in the liver leads to liver failure. Cholestasis can be caused by mutations in genes that code for proteins involved in bile secretion....

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Detalles Bibliográficos
Autores principales: Li, Qinghong, Sun, Yue, van IJzendoorn, Sven C. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914782/
https://www.ncbi.nlm.nih.gov/pubmed/33557414
http://dx.doi.org/10.3390/biology10020119