5-Bromoprotocatechualdehyde Combats against Palmitate Toxicity by Inhibiting Parkin Degradation and Reducing ROS-Induced Mitochondrial Damage in Pancreatic β-Cells

Pancreatic β-cell loss is critical in diabetes pathogenesis. Up to now, no effective treatment has become available for β-cell loss. A polyphenol recently isolated from Polysiphonia japonica, 5-Bromoprotocatechualdehyde (BPCA), is considered as a potential compound for the protection of β-cells. In...

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Detalles Bibliográficos
Autores principales: Cha, Seon-Heui, Zhang, Chunying, Heo, Soo-Jin, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914851/
https://www.ncbi.nlm.nih.gov/pubmed/33572166
http://dx.doi.org/10.3390/antiox10020264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914851/
https://www.ncbi.nlm.nih.gov/pubmed/33572166
http://dx.doi.org/10.3390/antiox10020264

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