Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis

CD137 is a costimulatory molecule expressed on activated T cells. CD137 ligand (CD137L) is expressed by antigen presenting cells (APC), which use the CD137—CD137L system to enhance immune responses. It was, therefore, surprising to discover CD137 expression on regulatory T cells (Treg). The function...

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Detalles Bibliográficos
Autores principales: Luu, Khang, Patwardhan, Mugdha Vijay, Zeng, Qun, Wickström, Stina L., Lundqvist, Andreas, Schwarz, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914903/
https://www.ncbi.nlm.nih.gov/pubmed/33572150
http://dx.doi.org/10.3390/cells10020353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914903/
https://www.ncbi.nlm.nih.gov/pubmed/33572150
http://dx.doi.org/10.3390/cells10020353

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