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The Structure, Activation and Signaling of IRE1 and Its Role in Determining Cell Fate

Inositol-requiring enzyme type 1 (IRE1) is a serine/threonine kinase acting as one of three branches of the Unfolded Protein Response (UPR) signaling pathway, which is activated upon endoplasmic reticulum (ER) stress conditions. It is known to be capable of inducing both pro-survival and pro-apoptot...

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Detalles Bibliográficos
Autores principales:	Siwecka, Natalia, Rozpędek-Kamińska, Wioletta, Wawrzynkiewicz, Adam, Pytel, Dariusz, Diehl, J. Alan, Majsterek, Ireneusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914947/ https://www.ncbi.nlm.nih.gov/pubmed/33562589 http://dx.doi.org/10.3390/biomedicines9020156

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