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A Novel Artificially Humanized Anti-Cripto-1 Antibody Suppressing Cancer Cell Growth

Cripto-1 is a member of the EGF-CFC/FRL1/Cryptic family and is involved in embryonic development and carcinogenesis. We designed a novel anti-Cripto-1 artificial antibody and assessed the recognition to the antigen and the potential to suppress the growth of cancer stem cells. First, single chain an...

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Detalles Bibliográficos
Autores principales: Ishii, Hiroko, Zahra, Maram H., Takayanagi, Atushi, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915030/
https://www.ncbi.nlm.nih.gov/pubmed/33567764
http://dx.doi.org/10.3390/ijms22041709

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