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Molecular and Cellular Effects of Chemical Chaperone—TUDCA on ER-Stressed NHAC-kn Human Articular Chondrocytes Cultured in Normoxic and Hypoxic Conditions

Osteoarthritis (OA) is considered one of the most common arthritic diseases characterized by progressive degradation and abnormal remodeling of articular cartilage. Potential therapeutics for OA aim at restoring proper chondrocyte functioning and inhibiting apoptosis. Previous studies have demonstra...

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Detalles Bibliográficos
Autores principales: Kusaczuk, Magdalena, Naumowicz, Monika, Krętowski, Rafał, Cukierman, Bartosz, Cechowska-Pasko, Marzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915106/
https://www.ncbi.nlm.nih.gov/pubmed/33562298
http://dx.doi.org/10.3390/molecules26040878

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