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Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis

The exponential growth in the use of dental implants in the last decades has been accompanied by an increase in the prevalence of peri-implant disease. It appears that viruses may have pathogenic potential for the development of this pathology. The objective of this systematic review is to study the...

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Autores principales: Roca-Millan, Elisabet, Domínguez-Mínger, Judith, Schemel-Suárez, Mayra, Estrugo-Devesa, Albert, Marí-Roig, Antonio, López-López, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915238/
https://www.ncbi.nlm.nih.gov/pubmed/33562820
http://dx.doi.org/10.3390/v13020250
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author Roca-Millan, Elisabet
Domínguez-Mínger, Judith
Schemel-Suárez, Mayra
Estrugo-Devesa, Albert
Marí-Roig, Antonio
López-López, José
author_facet Roca-Millan, Elisabet
Domínguez-Mínger, Judith
Schemel-Suárez, Mayra
Estrugo-Devesa, Albert
Marí-Roig, Antonio
López-López, José
author_sort Roca-Millan, Elisabet
collection PubMed
description The exponential growth in the use of dental implants in the last decades has been accompanied by an increase in the prevalence of peri-implant disease. It appears that viruses may have pathogenic potential for the development of this pathology. The objective of this systematic review is to study the possible association between the presence of Epstein–Barr virus and the development of peri-implantitis. An electronic search was conducted in PubMed/MEDLINE, Scielo and Embase databases for cross-sectional and case–control studies in humans published up to and including 4 January 2021. Five studies were included in the qualitative analysis. The meta-analysis did not show a statistically significant difference regarding the prevalence of Epstein–Barr virus in the peri-implant sulcus between implants with peri-implantitis and healthy implants. In conclusion, no association between the human herpesvirus 4 and peri-implantitis was found. Further research on this topic is essential to develop more effective treatments.
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spelling pubmed-79152382021-03-01 Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis Roca-Millan, Elisabet Domínguez-Mínger, Judith Schemel-Suárez, Mayra Estrugo-Devesa, Albert Marí-Roig, Antonio López-López, José Viruses Review The exponential growth in the use of dental implants in the last decades has been accompanied by an increase in the prevalence of peri-implant disease. It appears that viruses may have pathogenic potential for the development of this pathology. The objective of this systematic review is to study the possible association between the presence of Epstein–Barr virus and the development of peri-implantitis. An electronic search was conducted in PubMed/MEDLINE, Scielo and Embase databases for cross-sectional and case–control studies in humans published up to and including 4 January 2021. Five studies were included in the qualitative analysis. The meta-analysis did not show a statistically significant difference regarding the prevalence of Epstein–Barr virus in the peri-implant sulcus between implants with peri-implantitis and healthy implants. In conclusion, no association between the human herpesvirus 4 and peri-implantitis was found. Further research on this topic is essential to develop more effective treatments. MDPI 2021-02-05 /pmc/articles/PMC7915238/ /pubmed/33562820 http://dx.doi.org/10.3390/v13020250 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Roca-Millan, Elisabet
Domínguez-Mínger, Judith
Schemel-Suárez, Mayra
Estrugo-Devesa, Albert
Marí-Roig, Antonio
López-López, José
Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title_full Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title_fullStr Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title_full_unstemmed Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title_short Epstein–Barr Virus and Peri-Implantitis: A Systematic Review and Meta-Analysis
title_sort epstein–barr virus and peri-implantitis: a systematic review and meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915238/
https://www.ncbi.nlm.nih.gov/pubmed/33562820
http://dx.doi.org/10.3390/v13020250
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