Biochemical and Computational Studies of the Interaction between a Glucosamine Derivative, NAPA, and the IKKα Kinase

The glucosamine derivative 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy- [Formula: see text]-D-glucose (NAPA), was shown to inhibit the kinase activity of IKK [Formula: see text] , one of the two catalytic subunits of IKK complex, decreasing the inflammatory status in osteoarthritis chondrocytes. In the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopreiato, Mariangela, Di Cristofano, Samuele, Cocchiola, Rossana, Mariano, Alessia, Guerrizio, Libera, Scandurra, Roberto, Mosca, Luciana, Raimondo, Domenico, d’Abusco, Anna Scotto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915277/
https://www.ncbi.nlm.nih.gov/pubmed/33562013
http://dx.doi.org/10.3390/ijms22041643

Ejemplares similares

Ejemplares similares