Transcriptomic Analyses of MYCN-Regulated Genes in Anaplastic Wilms’ Tumour Cell Lines Reveals Oncogenic Pathways and Potential Therapeutic Vulnerabilities

SIMPLE SUMMARY: Wilms’ tumour (WT) is one of the most common solid paediatric malignancies and arises in the developing kidney. Treatment of most WTs is relatively successful, with the notable exception of tumours with anaplastic histology. Anaplastic WT survival rates can be as low as 30–50%, empha...

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Detalles Bibliográficos
Autores principales: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Park, Ji Hyun, Chen, Biyao, Greenhough, Alexander, Catchpoole, Daniel, Malik, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915280/
https://www.ncbi.nlm.nih.gov/pubmed/33562123
http://dx.doi.org/10.3390/cancers13040656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915280/
https://www.ncbi.nlm.nih.gov/pubmed/33562123
http://dx.doi.org/10.3390/cancers13040656

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