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Transcriptomic Analyses of MYCN-Regulated Genes in Anaplastic Wilms’ Tumour Cell Lines Reveals Oncogenic Pathways and Potential Therapeutic Vulnerabilities
SIMPLE SUMMARY: Wilms’ tumour (WT) is one of the most common solid paediatric malignancies and arises in the developing kidney. Treatment of most WTs is relatively successful, with the notable exception of tumours with anaplastic histology. Anaplastic WT survival rates can be as low as 30–50%, empha...
Autores principales: | Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Park, Ji Hyun, Chen, Biyao, Greenhough, Alexander, Catchpoole, Daniel, Malik, Karim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915280/ https://www.ncbi.nlm.nih.gov/pubmed/33562123 http://dx.doi.org/10.3390/cancers13040656 |
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