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Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach

Preoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to dif...

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Autores principales: Reginelli, Alfonso, Clemente, Alfredo, Sangiovanni, Angelo, Nardone, Valerio, Selvaggi, Francesco, Sciaudone, Guido, Ciardiello, Fortunato, Martinelli, Erika, Grassi, Roberto, Cappabianca, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915333/
https://www.ncbi.nlm.nih.gov/pubmed/33567516
http://dx.doi.org/10.3390/jcm10040641
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author Reginelli, Alfonso
Clemente, Alfredo
Sangiovanni, Angelo
Nardone, Valerio
Selvaggi, Francesco
Sciaudone, Guido
Ciardiello, Fortunato
Martinelli, Erika
Grassi, Roberto
Cappabianca, Salvatore
author_facet Reginelli, Alfonso
Clemente, Alfredo
Sangiovanni, Angelo
Nardone, Valerio
Selvaggi, Francesco
Sciaudone, Guido
Ciardiello, Fortunato
Martinelli, Erika
Grassi, Roberto
Cappabianca, Salvatore
author_sort Reginelli, Alfonso
collection PubMed
description Preoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to different therapeutic options. In particular, potential pitfalls may occur in the assessment of T3 tumors, which represents the most common stage at diagnosis. The depth of tumor invasion is known to be an important prognostic factor in rectal carcinoma; as a consequence, the T3 imaging classification has a substantial importance for treatment strategy and patient survival. However, the differentiation between tumor invasion of perirectal fat and mesorectal desmoplastic reactions remains a main goal for radiologists. Magnetic resonance imaging (MRI) is actually considered as the best imaging modality for rectal cancer staging. Although the endorectal ultrasound (ERUS) is the preferred staging method for early tumors, it could also be useful in identifying perirectal fat invasion. Moreover, the addiction of diffusion weighted imaging (DWI) improves the diagnostic performance of MRI in rectal cancer staging by adding functional information about rectal tumor and adjacent mesorectal tissues. This study investigated the diagnostic performance of conventional MRI alone, in combination with the DWI technique and ERUS in order to assess the best diagnostic imaging combination for rectal cancer staging.
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spelling pubmed-79153332021-03-01 Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach Reginelli, Alfonso Clemente, Alfredo Sangiovanni, Angelo Nardone, Valerio Selvaggi, Francesco Sciaudone, Guido Ciardiello, Fortunato Martinelli, Erika Grassi, Roberto Cappabianca, Salvatore J Clin Med Article Preoperative staging represents a crucial point for the management, type of surgery, and candidacy for neoadjuvant therapy in patient with rectal cancer. The most recent clinical guidelines in oncology recommend an accurate preoperative evaluation in order to address early and advanced tumors to different therapeutic options. In particular, potential pitfalls may occur in the assessment of T3 tumors, which represents the most common stage at diagnosis. The depth of tumor invasion is known to be an important prognostic factor in rectal carcinoma; as a consequence, the T3 imaging classification has a substantial importance for treatment strategy and patient survival. However, the differentiation between tumor invasion of perirectal fat and mesorectal desmoplastic reactions remains a main goal for radiologists. Magnetic resonance imaging (MRI) is actually considered as the best imaging modality for rectal cancer staging. Although the endorectal ultrasound (ERUS) is the preferred staging method for early tumors, it could also be useful in identifying perirectal fat invasion. Moreover, the addiction of diffusion weighted imaging (DWI) improves the diagnostic performance of MRI in rectal cancer staging by adding functional information about rectal tumor and adjacent mesorectal tissues. This study investigated the diagnostic performance of conventional MRI alone, in combination with the DWI technique and ERUS in order to assess the best diagnostic imaging combination for rectal cancer staging. MDPI 2021-02-08 /pmc/articles/PMC7915333/ /pubmed/33567516 http://dx.doi.org/10.3390/jcm10040641 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Reginelli, Alfonso
Clemente, Alfredo
Sangiovanni, Angelo
Nardone, Valerio
Selvaggi, Francesco
Sciaudone, Guido
Ciardiello, Fortunato
Martinelli, Erika
Grassi, Roberto
Cappabianca, Salvatore
Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title_full Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title_fullStr Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title_full_unstemmed Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title_short Endorectal Ultrasound and Magnetic Resonance Imaging for Rectal Cancer Staging: A Modern Multimodality Approach
title_sort endorectal ultrasound and magnetic resonance imaging for rectal cancer staging: a modern multimodality approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915333/
https://www.ncbi.nlm.nih.gov/pubmed/33567516
http://dx.doi.org/10.3390/jcm10040641
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