Cargando…

Viral-Vector-Delivered Anti-Angiogenic Therapies to the Eye

Pathological vessel growth harms vision and may finally lead to vision loss. Anti-angiogenic gene therapy with viral vectors for ocular neovascularization has shown great promise in preclinical studies. Most of the studies have been conducted with different adeno-associated serotype vectors. In addi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koponen, Sanna, Kokki, Emmi, Kinnunen, Kati, Ylä-Herttuala, Seppo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915489/ https://www.ncbi.nlm.nih.gov/pubmed/33562561 http://dx.doi.org/10.3390/pharmaceutics13020219

Ejemplares similares

Human Vascular Endothelial Growth Factor A(165) Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration
por: Kokki, Emmi, et al.
Publicado: (2018)

Gene Therapy Used in Cancer Treatment
por: Wirth, Thomas, et al.
Publicado: (2014)

Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety
por: Leikas, Aleksi J., et al.
Publicado: (2023)

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production
por: Leinonen, Hanna M., et al.
Publicado: (2020)

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance T(RAFFn), T(1ρ) and T(2) relaxation times
por: Ylä-Herttuala, Elias, et al.
Publicado: (2023)

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus
por: Husso, Tiia, et al.
Publicado: (2014)

Therapeutic Potential of VEGF-B in Coronary Heart Disease and Heart Failure: Dream or Vision?
por: Mallick, Rahul, et al.
Publicado: (2022)

Characterization of a new IN-I-PpoI fusion protein and a homology-arm containing transgene cassette that improve transgene expression persistence and 28S rRNA gene-targeted insertion of lentiviral vectors
por: Nousiainen, Alisa, et al.
Publicado: (2023)

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer
por: Sallinen, Hanna, et al.
Publicado: (2014)

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success
por: Dragneva, Galina, et al.
Publicado: (2013)

Novel RNAi-Based Therapies for Atherosclerosis
por: Ruotsalainen, Anna-Kaisa, et al.
Publicado: (2021)

Nucleic Acid–Based Therapies for Atherosclerosis
por: Mäkinen, Petri, et al.
Publicado: (2020)

LDLR(–/–)ApoB(100/100) mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina
por: Kinnunen, Kati, et al.
Publicado: (2013)

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
por: Toivanen, Pyry I., et al.
Publicado: (2017)

COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs
por: Jiang, Miao, et al.
Publicado: (2023)

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
por: Vuorio, Taina, et al.
Publicado: (2018)

Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
por: Eriksson, Reetta A. E., et al.
Publicado: (2022)

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
por: Kivelä, Antti, et al.
Publicado: (2012)

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
por: Eriksson, Reetta A. E., et al.
Publicado: (2023)

Nephrotoxicity of Anti-Angiogenic Therapies
por: Van Wynsberghe, Margaux, et al.
Publicado: (2021)

Angiogenic signaling pathways and anti-angiogenic therapy for cancer
por: Liu, Zhen-Ling, et al.
Publicado: (2023)

SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice
por: Gurzeler, Erika, et al.
Publicado: (2021)

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts
por: Nilsson, Ingrid, et al.
Publicado: (2010)

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
por: Zurek, Michelle, et al.
Publicado: (2021)

Biomarkers for Anti-Angiogenic Therapy in Cancer
por: Wehland, Markus, et al.
Publicado: (2013)

Technological advances in the use of viral and non-viral vectors for delivering genetic and non-genetic cargos for cancer therapy
por: Dogbey, Dennis Makafui, et al.
Publicado: (2023)

AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice
por: Kujala, Anni, et al.
Publicado: (2022)

Experimental Evaluation of an Interferometric Light Microscopy Particle Counter for Titering and Characterization of Virus Preparations
por: Turkki, Vesa, et al.
Publicado: (2021)

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs
por: Laham-Karam, Nihay, et al.
Publicado: (2015)

Editorial: Vascularization for Regenerative Medicine
por: Banfi, Andrea, et al.
Publicado: (2018)

Anti-angiogenic therapies in brain metastases
por: Berghoff, Anna S., et al.
Publicado: (2018)

Prospects for Foamy Viral Vector Anti-HIV Gene Therapy
por: Nalla, Arun K., et al.
Publicado: (2016)

Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products
por: Gurvich, Olga L., et al.
Publicado: (2020)

Recent Advances in Anti-Angiogenic Therapy of Cancer
por: Samant, Rajeev S., et al.
Publicado: (2011)

Biomarkers in Tumor Angiogenesis and Anti-Angiogenic Therapy
por: Pircher, Andreas, et al.
Publicado: (2011)

Future options of anti-angiogenic cancer therapy
por: Cao, Yihai
Publicado: (2016)

Angiogenesis and Anti-Angiogenic Therapy in Gastric Cancer
por: Nienhüser, Henrik, et al.
Publicado: (2017)

Exosomes in Angiogenesis and Anti-angiogenic Therapy in Cancers
por: Olejarz, Wioletta, et al.
Publicado: (2020)

Trends and Challenges in Tumor Anti-Angiogenic Therapies
por: Jászai, József, et al.
Publicado: (2019)

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
por: Gallini, Radiosa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iu9ll0ca5si69re5nstt8vpdkb