Cargando…

Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling

The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease has become a major health problem. Oxidative stress (OS) plays an important role in the pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant responsive element (ARE) antiox...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uddin, Md Jamal, Kim, Ee Hyun, Hannan, Md. Abdul, Ha, Hunjoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915495/ https://www.ncbi.nlm.nih.gov/pubmed/33562389 http://dx.doi.org/10.3390/antiox10020258

Ejemplares similares

Prospective Pharmacological Potential of Resveratrol in Delaying Kidney Aging
por: Uddin, Md Jamal, et al.
Publicado: (2021)

Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress
por: Uddin, Md Jamal, et al.
Publicado: (2018)

Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights
por: Hannan, Md. Abdul, et al.
Publicado: (2021)

CO-Releasing Molecule-2 Prevents Acute Kidney Injury through Suppression of ROS-Fyn-ER Stress Signaling in Mouse Model
por: Uddin, Md Jamal, et al.
Publicado: (2021)

Renoprotective potentials of small molecule natural products targeting mitochondrial dysfunction
por: Rahman, Md. Ataur, et al.
Publicado: (2022)

Inhibition of Src Family Kinases Ameliorates LPS-Induced Acute Kidney Injury and Mitochondrial Dysfunction in Mice
por: Pak, Eun Seon, et al.
Publicado: (2020)

Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury
por: Uddin, Md Jamal, et al.
Publicado: (2020)

Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances
por: Zahan, Md. Sarwar, et al.
Publicado: (2022)

PGC‐1α, a potential therapeutic target against kidney aging
por: Lee, Gayoung, et al.
Publicado: (2019)

Prospects of Marine Sterols against Pathobiology of Alzheimer’s Disease: Pharmacological Insights and Technological Advances
por: Rahman, Md. Ataur, et al.
Publicado: (2021)

Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19
por: Farjana, Mithila, et al.
Publicado: (2020)

Prospects of honey in fighting against COVID-19: pharmacological insights and therapeutic promises
por: Hossain, Khandkar Shaharina, et al.
Publicado: (2020)

Prospects for Protective Potential of Moringa oleifera against Kidney Diseases
por: Akter, Tanzina, et al.
Publicado: (2021)

Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model
por: Jeong, Bo Yeong, et al.
Publicado: (2016)

Emerging Signal Regulating Potential of Genistein Against Alzheimer’s Disease: A Promising Molecule of Interest
por: Uddin, Md. Sahab, et al.
Publicado: (2019)

Modulation of Nrf2/HO-1 by Natural Compounds in Lung Cancer
por: Ghareghomi, Somayyeh, et al.
Publicado: (2023)

Editorial: Novel pharmacological approaches targeting mitochondrial dysfunction in diseases
por: Uddin, Md. Jamal, et al.
Publicado: (2022)

Novel Role of Endogenous Catalase in Macrophage Polarization in Adipose Tissue
por: Park, Ye Seul, et al.
Publicado: (2016)

An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1
por: Rahman, MD. Hasanur, et al.
Publicado: (2022)

Natural Small Molecules Targeting NF-κB Signaling in Glioblastoma
por: Uddin, Md. Sahab, et al.
Publicado: (2021)

Changes of renal histopathology and the role of Nrf2/HO-1 in asphyxial cardiac arrest model in rats
por: Jawad, Ali, et al.
Publicado: (2021)

Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice
por: Jiang, Songling, et al.
Publicado: (2022)

Exposure to Environmental Arsenic and Emerging Risk of Alzheimer’s Disease: Perspective Mechanisms, Management Strategy, and Future Directions
por: Rahman, Md. Ataur, et al.
Publicado: (2021)

Editorial: Pharmacotherapy of Anxiety Disorders: Promises and Pitfalls
por: Garakani, Amir, et al.
Publicado: (2021)

Fuzhuan Brick Tea Boosts Melanogenesis and Prevents Hair Graying through Reduction of Oxidative Stress via NRF2-HO-1 Signaling
por: Zhao, Peijun, et al.
Publicado: (2022)

Cerevisterol Alleviates Inflammation via Suppression of MAPK/NF-κB/AP-1 and Activation of the Nrf2/HO-1 Signaling Cascade
por: Alam, Md Badrul, et al.
Publicado: (2020)

Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System
por: Hannan, Md. Abdul, et al.
Publicado: (2020)

Nrf2 Activation in Chronic Kidney Disease: Promises and Pitfalls
por: Aranda-Rivera, Ana Karina, et al.
Publicado: (2022)

Kidney Drug Transporters in Pharmacotherapy
por: Łapczuk-Romańska, Joanna, et al.
Publicado: (2023)

Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO‐1 pathway
por: Huang, Qi, et al.
Publicado: (2021)

Potential Therapeutic Role of Phytochemicals to Mitigate Mitochondrial Dysfunctions in Alzheimer’s Disease
por: Rahman, Md. Ataur, et al.
Publicado: (2020)

Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives
por: Akter, Sumaya, et al.
Publicado: (2022)

Advances in Biosynthesis, Pharmacology, and Pharmacokinetics of Pinocembrin, a Promising Natural Small-Molecule Drug
por: Shen, Xiaoling, et al.
Publicado: (2019)

p53 Modulation of Autophagy Signaling in Cancer Therapies: Perspectives Mechanism and Therapeutic Targets
por: Rahman, Md Ataur, et al.
Publicado: (2022)

Inhibitory Role of the KEAP1-NRF2 Pathway in TGFβ1-Stimulated Renal Epithelial Transition to Fibroblastic Cells: A Modulatory Effect on SMAD Signaling
por: Ryoo, In-geun, et al.
Publicado: (2014)

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems
por: Baldim, Iara, et al.
Publicado: (2020)

A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis
por: Kwon, Guideock, et al.
Publicado: (2017)

Glucokinase activators (GKAs) promise a new pharmacotherapy for diabetics
por: Matschinsky, Franz M, et al.
Publicado: (2010)

Ethnopharmacological Inspections of Organic Extract of Oroxylum indicum in Rat Models: A Promising Natural Gift
por: Begum, Mst. Marium, et al.
Publicado: (2019)

Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases
por: Mansouri, Atena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dsdfj6gjh5enkug3vu2d61vqnc