The Identification of Small Molecule Inhibitors That Reduce Invasion and Metastasis of Aggressive Cancers

Transformed epithelial cells can activate programs of epithelial plasticity and switch from a sessile, epithelial phenotype to a motile, mesenchymal phenotype. This process is linked to the acquisition of an invasive phenotype and the formation of distant metastases. The development of compounds tha...

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Detalles Bibliográficos
Autores principales: van de Merbel, Arjanneke F., van Hooij, Onno, van der Horst, Geertje, van Rijt-van de Westerlo, Cindy C. M., van der Mark, Maaike H., Cheung, Henry, Kroon, Jan, Verhaegh, Gerald W., Tijhuis, Johan, Wellink, Antoine, Maas, Peter, Viëtor, Henk, Schalken, Jack A., van der Pluijm, Gabri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915539/
https://www.ncbi.nlm.nih.gov/pubmed/33567533
http://dx.doi.org/10.3390/ijms22041688

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