Pursuing Orally Bioavailable Hepcidin Analogues via Cyclic N-Methylated Mini-Hepcidins

The peptide hormone hepcidin is one of the key regulators of iron absorption, plasma iron levels, and tissue iron distribution. Hepcidin functions by binding to and inducing the internalisation and subsequent lysosomal degradation of ferroportin, which reduces both iron absorption in the gut and exp...

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Detalles Bibliográficos
Autores principales: Goncalves Monteiro, Daniela, van Dijk, Johannes W. A., Aliyanto, Randy, Fung, Eileen, Nemeth, Elizabeta, Ganz, Tomas, Rosengren, Johan, Clark, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915682/
https://www.ncbi.nlm.nih.gov/pubmed/33567510
http://dx.doi.org/10.3390/biomedicines9020164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915682/
https://www.ncbi.nlm.nih.gov/pubmed/33567510
http://dx.doi.org/10.3390/biomedicines9020164

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