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Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis—An In Vitro Study

The high incidence of skin cancers in the Caucasian population is primarily due to the accumulation of DNA damage in epidermal cells induced by chronic ultraviolet B (UVB) exposure. UVB-induced DNA photolesions, including cyclobutane–pyrimidine dimers (CPDs), promote mutations in skin cancer driver...

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Detalles Bibliográficos
Autores principales: Fidrus, Eszter, Hegedűs, Csaba, Janka, Eszter Anna, Paragh, György, Emri, Gabriella, Remenyik, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915687/
https://www.ncbi.nlm.nih.gov/pubmed/33562002
http://dx.doi.org/10.3390/ijms22041638

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