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Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis

Chronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS)....

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Autores principales: Cepeha, Cristina Mihaela, Paul, Corina, Borlea, Andreea, Fofiu, Renata, Borcan, Florin, Dehelean, Cristina Adriana, Ivan, Viviana, Stoian, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915688/
https://www.ncbi.nlm.nih.gov/pubmed/33562689
http://dx.doi.org/10.3390/diagnostics11020248
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author Cepeha, Cristina Mihaela
Paul, Corina
Borlea, Andreea
Fofiu, Renata
Borcan, Florin
Dehelean, Cristina Adriana
Ivan, Viviana
Stoian, Dana
author_facet Cepeha, Cristina Mihaela
Paul, Corina
Borlea, Andreea
Fofiu, Renata
Borcan, Florin
Dehelean, Cristina Adriana
Ivan, Viviana
Stoian, Dana
author_sort Cepeha, Cristina Mihaela
collection PubMed
description Chronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS). This study aims to assess its use also in detecting children with CAT. The study group consisted of 50 children with confirmed diagnosis of CAT, who were compared to the control group, consisting of 50 children with no thyroid pathology and with an adult group of 50 subjects with CAT. The evaluation included, besides bioimmunochemical evaluation, also thyroid ultrasound evaluation and elastography measurements in the same session (Aixplorer Mach 30, Supersonic imagine, France). The mean TS values were significantly lower for children in the CAT group compared to adults with CAT (15.51 ± 4.76 kPa vs. 20.96 ± 6.31 kPa; p < 0.0001) and higher compared to the healthy aged matched controls (15.51 ± 4.76 kPa vs. 10.41 ± 2.01 kPa; p < 0.0001). SWE elastography definitely seems a promising technique in the evaluation of children with autoimmune thyroid pathology.
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spelling pubmed-79156882021-03-01 Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis Cepeha, Cristina Mihaela Paul, Corina Borlea, Andreea Fofiu, Renata Borcan, Florin Dehelean, Cristina Adriana Ivan, Viviana Stoian, Dana Diagnostics (Basel) Article Chronic autoimmune thyroiditis (CAT) is the most common thyroid disorder in the pediatric population. Ultrasound evaluation may suggest the diagnosis. Additionally, shear-wave elastography (SWE) proved to be a valuable additional diagnosis tool in adults with CAT by assessing thyroid stiffness (TS). This study aims to assess its use also in detecting children with CAT. The study group consisted of 50 children with confirmed diagnosis of CAT, who were compared to the control group, consisting of 50 children with no thyroid pathology and with an adult group of 50 subjects with CAT. The evaluation included, besides bioimmunochemical evaluation, also thyroid ultrasound evaluation and elastography measurements in the same session (Aixplorer Mach 30, Supersonic imagine, France). The mean TS values were significantly lower for children in the CAT group compared to adults with CAT (15.51 ± 4.76 kPa vs. 20.96 ± 6.31 kPa; p < 0.0001) and higher compared to the healthy aged matched controls (15.51 ± 4.76 kPa vs. 10.41 ± 2.01 kPa; p < 0.0001). SWE elastography definitely seems a promising technique in the evaluation of children with autoimmune thyroid pathology. MDPI 2021-02-05 /pmc/articles/PMC7915688/ /pubmed/33562689 http://dx.doi.org/10.3390/diagnostics11020248 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cepeha, Cristina Mihaela
Paul, Corina
Borlea, Andreea
Fofiu, Renata
Borcan, Florin
Dehelean, Cristina Adriana
Ivan, Viviana
Stoian, Dana
Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title_full Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title_fullStr Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title_full_unstemmed Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title_short Shear-Wave Elastography—Diagnostic Value in Children with Chronic Autoimmune Thyroiditis
title_sort shear-wave elastography—diagnostic value in children with chronic autoimmune thyroiditis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915688/
https://www.ncbi.nlm.nih.gov/pubmed/33562689
http://dx.doi.org/10.3390/diagnostics11020248
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