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Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome

Human adenoviruses (HAdVs) display a wide range of tissue tropism and can cause an array of symptoms from mild respiratory illnesses to disseminated and life-threatening infections in immunocompromised individuals. However, no antiviral drug has been approved specifically for the treatment of HAdV i...

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Detalles Bibliográficos
Autores principales: Xu, Jimin, Berastegui-Cabrera, Judith, Carretero-Ledesma, Marta, Chen, Haiying, Xue, Yu, Wold, Eric A., Pachón, Jerónimo, Zhou, Jia, Sánchez-Céspedes, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915867/
https://www.ncbi.nlm.nih.gov/pubmed/33562748
http://dx.doi.org/10.3390/ijms22041617