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Synthesis, Antitumor and Antibacterial Studies of New Shortened Analogues of (KLAKLAK)(2)-NH(2) and Their Conjugates Containing Unnatural Amino Acids

(1) Background: (KLAKLAK)(2) is a representative of the antimicrobial peptide group which also shows good anticancer properties. (2) Methods: Herein, we report synthesis using SPPS and characterization by HPLC/MS of a series of shortened analogues of (KLAKLAK)(2). They contain single sequence KLAKLA...

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Detalles Bibliográficos
Autores principales: Jaber, Sirine, Iliev, Ivan, Angelova, Tsvetelina, Nemska, Veronica, Sulikovska, Inna, Naydenova, Emilia, Georgieva, Nelly, Givechev, Ivan, Grabchev, Ivo, Danalev, Dancho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915940/
https://www.ncbi.nlm.nih.gov/pubmed/33567789
http://dx.doi.org/10.3390/molecules26040898