Targeting Beclin1 as an Adjunctive Therapy against HIV Using Mannosylated Polyethylenimine Nanoparticles

Using nanoparticle-based RNA interference (RNAi), we have previously shown that silencing the host autophagic protein, Beclin1, in HIV-infected human microglia and astrocytes restricts HIV replication and its viral-associated inflammatory responses. Here, we confirmed the efficacy of Beclin1 small i...

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Detalles Bibliográficos
Autores principales: Rodriguez, Myosotys, Soler, Yemmy, Muthu Karuppan, Mohan Kumar, Zhao, Yuling, Batrakova, Elena V., El-Hage, Nazira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915950/
https://www.ncbi.nlm.nih.gov/pubmed/33561939
http://dx.doi.org/10.3390/pharmaceutics13020223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915950/
https://www.ncbi.nlm.nih.gov/pubmed/33561939
http://dx.doi.org/10.3390/pharmaceutics13020223

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