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Conjugation of Mannans to Enhance the Potency of Liposome Nanoparticles for the Delivery of RNA Vaccines

Recent approval of mRNA vaccines to combat COVID-19 have highlighted the potential of this platform. Lipid nanoparticles (LNP) is the delivery vehicle of choice for mRNA as they prevent its enzymatic degradation by encapsulation. We have recently shown that surface exposition of mannose, incorporate...

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Detalles Bibliográficos
Autores principales: Goswami, Roshan, O’Hagan, Derek T., Adamo, Roberto, Baudner, Barbara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916126/
https://www.ncbi.nlm.nih.gov/pubmed/33572332
http://dx.doi.org/10.3390/pharmaceutics13020240