Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism

LAT is an important player of the signaling cascade induced by TCR activation. This adapter molecule is present at the plasma membrane of T lymphocytes and more abundantly in intracellular compartments. Upon T cell activation the intracellular pool of LAT is recruited to the immune synapse (IS). We...

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Detalles Bibliográficos
Autores principales: Saez, Juan José, Dogniaux, Stephanie, Shafaq-Zadah, Massiullah, Johannes, Ludger, Hivroz, Claire, Zucchetti, Andrés Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916135/
https://www.ncbi.nlm.nih.gov/pubmed/33572370
http://dx.doi.org/10.3390/cells10020359

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