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Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging

Burn injuries constitute a critical economic burden on healthcare infrastructures worldwide. They are often associated with high mortality rates due to severe complications. Infection is the most common complication, highlighting the importance of prompt and precise diagnosis in order to prevent det...

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Detalles Bibliográficos
Autores principales: Farhan, Nawras, Jeffery, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916143/
https://www.ncbi.nlm.nih.gov/pubmed/33572369
http://dx.doi.org/10.3390/diagnostics11020268
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author Farhan, Nawras
Jeffery, Steven
author_facet Farhan, Nawras
Jeffery, Steven
author_sort Farhan, Nawras
collection PubMed
description Burn injuries constitute a critical economic burden on healthcare infrastructures worldwide. They are often associated with high mortality rates due to severe complications. Infection is the most common complication, highlighting the importance of prompt and precise diagnosis in order to prevent detrimental consequences and to optimize patient outcomes. Here we examine the current standard of care for diagnosing infection in both burn and chronic wounds followed by an investigation into the research surrounding a relatively new technique for bacterial detection, fluorescence imaging. With five years of published research on bacterial fluorescence imaging (MolecuLight i:X device), we have summarized and analysed the validity of the procedure and compared it to the current standard of care; clinical assessment and microbiological analysis. We highlight the benefits that could be obtained through the use of this technology as well as the limitations and the feasibility of incorporating this novel procedure into the standard of care.
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spelling pubmed-79161432021-03-01 Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging Farhan, Nawras Jeffery, Steven Diagnostics (Basel) Review Burn injuries constitute a critical economic burden on healthcare infrastructures worldwide. They are often associated with high mortality rates due to severe complications. Infection is the most common complication, highlighting the importance of prompt and precise diagnosis in order to prevent detrimental consequences and to optimize patient outcomes. Here we examine the current standard of care for diagnosing infection in both burn and chronic wounds followed by an investigation into the research surrounding a relatively new technique for bacterial detection, fluorescence imaging. With five years of published research on bacterial fluorescence imaging (MolecuLight i:X device), we have summarized and analysed the validity of the procedure and compared it to the current standard of care; clinical assessment and microbiological analysis. We highlight the benefits that could be obtained through the use of this technology as well as the limitations and the feasibility of incorporating this novel procedure into the standard of care. MDPI 2021-02-09 /pmc/articles/PMC7916143/ /pubmed/33572369 http://dx.doi.org/10.3390/diagnostics11020268 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Farhan, Nawras
Jeffery, Steven
Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title_full Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title_fullStr Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title_full_unstemmed Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title_short Diagnosing Burn Wounds Infection: The Practice Gap & Advances with MolecuLight Bacterial Imaging
title_sort diagnosing burn wounds infection: the practice gap & advances with moleculight bacterial imaging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916143/
https://www.ncbi.nlm.nih.gov/pubmed/33572369
http://dx.doi.org/10.3390/diagnostics11020268
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