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The Identity of PDGFRA D842V-Mutant Gastrointestinal Stromal Tumors (GIST)

SIMPLE SUMMARY: Among the platelet-derived growth factor receptor (PDGFRA) mutations in gastrointestinal stromal tumors (GIST), the most frequent is the substitution at position 842 in the A-loop of an aspartic acid (D) with a valine (V), widely recognized as D842V, a two-sided mutation providing pr...

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Detalles Bibliográficos
Autores principales:	Rizzo, Alessandro, Pantaleo, Maria Abbondanza, Astolfi, Annalisa, Indio, Valentina, Nannini, Margherita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916155/ https://www.ncbi.nlm.nih.gov/pubmed/33572358 http://dx.doi.org/10.3390/cancers13040705

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