High lymphocyte population-related predictive factors for a long-term response in non-small cell lung cancer patients treated with pemetrexed: a retrospective observational study

BACKGROUND: Regimens combining pemetrexed (PEM) and immune checkpoint inhibitors (ICIs) targeting programmed cell death-1 (PD-1) or programmed death-ligand 1 (PD-L1) are widely used for the treatment of advanced non-squamous non-small-cell lung cancer (NSq-NSCLC). Recently, PEM was shown to induce i...

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Detalles Bibliográficos
Autores principales: Sumiyoshi, Issei, Okabe, Takahiro, Togo, Shinsaku, Takagi, Haruhi, Motomura, Hiroaki, Ochi, Yusuke, Shimada, Naoko, Haraguchi, Mizuki, Shibayama, Rina, Fujimoto, Yuichi, Watanabe, Junko, Iwai, Moe, Kadoya, Kotaro, Iwakami, Shin-ichiro, Takahashi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916269/
https://www.ncbi.nlm.nih.gov/pubmed/33639962
http://dx.doi.org/10.1186/s12967-021-02761-1

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