Hyper‐metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities

BACKGROUND: Aging is associated with increased intrinsic B cell inflammation, decreased protective antibody responses and increased autoimmune antibody responses. The effects of aging on the metabolic phenotype of B cells and on the metabolic programs that lead to the secretion of protective versus...

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Detalles Bibliográficos
Autores principales: Frasca, Daniela, Romero, Maria, Garcia, Denisse, Diaz, Alain, Blomberg, Bonnie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916295/
https://www.ncbi.nlm.nih.gov/pubmed/33639971
http://dx.doi.org/10.1186/s12979-021-00222-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916295/
https://www.ncbi.nlm.nih.gov/pubmed/33639971
http://dx.doi.org/10.1186/s12979-021-00222-3

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