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Hyper‐metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities
BACKGROUND: Aging is associated with increased intrinsic B cell inflammation, decreased protective antibody responses and increased autoimmune antibody responses. The effects of aging on the metabolic phenotype of B cells and on the metabolic programs that lead to the secretion of protective versus...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916295/ https://www.ncbi.nlm.nih.gov/pubmed/33639971 http://dx.doi.org/10.1186/s12979-021-00222-3 |