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Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice
The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old Tnfaip3(DNGR1-KO) mice develop pulmonary hypertension (PH) symptoms. These mice harbor...
Autores principales: | van Uden, Denise, Koudstaal, Thomas, van Hulst, Jennifer A. C., Bergen, Ingrid M., Gootjes, Chelsea, Morrell, Nicholas W., van Loo, Geert, von der Thüsen, Jan H., van den Bosch, Thierry P. P., Ghigna, Maria-Rosa, Perros, Frédéric, Montani, David, Kool, Mirjam, Boomars, Karin A., Hendriks, Rudi W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916474/ https://www.ncbi.nlm.nih.gov/pubmed/33578743 http://dx.doi.org/10.3390/ijms22041756 |
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