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Plant Natural Products: Promising Resources for Cancer Chemoprevention
Cancer is a major factor threatening human health and life safety, and there is a lack of safe and effective therapeutic drugs. Intervention and prevention in premalignant process are effective ways to reverse carcinogenesis and prevent cancer from occurring. Plant natural products are rich in sourc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916513/ https://www.ncbi.nlm.nih.gov/pubmed/33578780 http://dx.doi.org/10.3390/molecules26040933 |
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author | Ma, Li Zhang, Mengmeng Zhao, Rong Wang, Dan Ma, Yuerong Ai, Li |
author_facet | Ma, Li Zhang, Mengmeng Zhao, Rong Wang, Dan Ma, Yuerong Ai, Li |
author_sort | Ma, Li |
collection | PubMed |
description | Cancer is a major factor threatening human health and life safety, and there is a lack of safe and effective therapeutic drugs. Intervention and prevention in premalignant process are effective ways to reverse carcinogenesis and prevent cancer from occurring. Plant natural products are rich in sources and are a promising source for cancer chemoprevention. This article reviews the chemopreventive effects of natural products, especially focused on polyphenols, flavonoids, monoterpene and triterpenoids, sulfur compounds, and cellulose. Meanwhile, the main mechanisms include induction of apoptosis, antiproliferation and inhibition of metastasis are briefly summarized. In conclusion, this article provides evidence for natural products remaining a prominent source of cancer chemoprevention. |
format | Online Article Text |
id | pubmed-7916513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79165132021-03-01 Plant Natural Products: Promising Resources for Cancer Chemoprevention Ma, Li Zhang, Mengmeng Zhao, Rong Wang, Dan Ma, Yuerong Ai, Li Molecules Review Cancer is a major factor threatening human health and life safety, and there is a lack of safe and effective therapeutic drugs. Intervention and prevention in premalignant process are effective ways to reverse carcinogenesis and prevent cancer from occurring. Plant natural products are rich in sources and are a promising source for cancer chemoprevention. This article reviews the chemopreventive effects of natural products, especially focused on polyphenols, flavonoids, monoterpene and triterpenoids, sulfur compounds, and cellulose. Meanwhile, the main mechanisms include induction of apoptosis, antiproliferation and inhibition of metastasis are briefly summarized. In conclusion, this article provides evidence for natural products remaining a prominent source of cancer chemoprevention. MDPI 2021-02-10 /pmc/articles/PMC7916513/ /pubmed/33578780 http://dx.doi.org/10.3390/molecules26040933 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ma, Li Zhang, Mengmeng Zhao, Rong Wang, Dan Ma, Yuerong Ai, Li Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title | Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title_full | Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title_fullStr | Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title_full_unstemmed | Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title_short | Plant Natural Products: Promising Resources for Cancer Chemoprevention |
title_sort | plant natural products: promising resources for cancer chemoprevention |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916513/ https://www.ncbi.nlm.nih.gov/pubmed/33578780 http://dx.doi.org/10.3390/molecules26040933 |
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