Cargando…

Unraveling the Molecular Tumor-Promoting Regulation of Cofilin-1 in Pancreatic Cancer

SIMPLE SUMMARY: Unraveling the mechanistic regulations that influence tumor behavior is an important step towards treatment. However, in vitro studies capture only small parts of the complex signaling cascades leading to tumor development. Mechanistic modeling, instead, allows a more holistic view o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Werle, Silke D., Schwab, Julian D., Tatura, Marina, Kirchhoff, Sandra, Szekely, Robin, Diels, Ramona, Ikonomi, Nensi, Sipos, Bence, Sperveslage, Jan, Gress, Thomas M., Buchholz, Malte, Kestler, Hans A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916621/ https://www.ncbi.nlm.nih.gov/pubmed/33578795 http://dx.doi.org/10.3390/cancers13040725

Ejemplares similares

Reconstructing Boolean network ensembles from single-cell data for unraveling dynamics in the aging of human hematopoietic stem cells
por: Schwab, Julian D., et al.
Publicado: (2021)

Awakening the HSC: Dynamic Modeling of HSC Maintenance Unravels Regulation of the TP53 Pathway and Quiescence
por: Ikonomi, Nensi, et al.
Publicado: (2020)

A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective
por: Werle, Silke D., et al.
Publicado: (2023)

Capturing dynamic relevance in Boolean networks using graph theoretical measures
por: Weidner, Felix M, et al.
Publicado: (2021)

Response to the letter to the editor: On the feasibility of dynamical analysis of network models of biochemical regulation
por: Weidner, Felix M, et al.
Publicado: (2022)

CANTATA—prediction of missing links in Boolean networks using genetic programming
por: Müssel, Christoph, et al.
Publicado: (2022)

Concepts in Boolean network modeling: What do they all mean?
por: Schwab, Julian D., et al.
Publicado: (2020)

Interaction Empowerment in Mobile Health: Concepts, Challenges, and Perspectives
por: Hamberger, Marietta, et al.
Publicado: (2022)

Leveraging quantum computing for dynamic analyses of logical networks in systems biology
por: Weidner, Felix M., et al.
Publicado: (2023)

A Multistep High-Content Screening Approach to Identify Novel Functionally Relevant Target Genes in Pancreatic Cancer
por: Buchholz, Malte, et al.
Publicado: (2015)

Supporting Medical Staff from Psycho-Oncology with Smart Mobile Devices: Insights into the Development Process and First Results
por: Schobel, Johannes, et al.
Publicado: (2021)

Identification of dynamic driver sets controlling phenotypical landscapes()
por: Werle, Silke D., et al.
Publicado: (2022)

Digitalization of adverse event management in oncology to improve treatment outcome—A prospective study protocol
por: Kestler, Angelika M. R., et al.
Publicado: (2021)

Patient Empowerment During the COVID-19 Pandemic by Ensuring Safe and Fast Communication of Test Results: Implementation and Performance of a Tracking System
por: Völkel, Gunnar, et al.
Publicado: (2021)

Metadata Correction: Patient Empowerment During the COVID-19 Pandemic by Ensuring Safe and Fast Communication of Test Results: Implementation and Performance of a Tracking System
por: Völkel, Gunnar, et al.
Publicado: (2021)

Unravelling the Biology of EhActo as the First Cofilin From Entamoeba histolytica
por: Kumar, Nitesh, et al.
Publicado: (2022)

Erratum to: Analysis, identification and visualization of subgroups in genomics
por: Völkel, Gunnar, et al.
Publicado: (2021)

Analysis, identification and visualization of subgroups in genomics
por: Völkel, Gunnar, et al.
Publicado: (2020)

Combined microRNA and mRNA microfluidic TaqMan array cards for the diagnosis of malignancy of multiple types of pancreatico-biliary tumors in fine-needle aspiration material
por: Gress, Thomas M., et al.
Publicado: (2017)

The POLD1(R689W) variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors
por: Job, Albert, et al.
Publicado: (2020)

Dissecting the role of toll‐like receptor 7 in pancreatic cancer
por: Stark, Maren, et al.
Publicado: (2023)

Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation
por: Goyal, Pankaj, et al.
Publicado: (2013)

Screening Technologies for Target Identification in Pancreatic Cancer
por: Michl, Patrick, et al.
Publicado: (2010)

Automatic Screening for Perturbations in Boolean Networks
por: Schwab, Julian D., et al.
Publicado: (2018)

How to engage Cofilin
por: Bukrinsky, Michael
Publicado: (2008)

A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia
por: Nagata-Ohashi, Kyoko, et al.
Publicado: (2004)

Cofilin-1 and Other ADF/Cofilin Superfamily Members in Human Malignant Cells
por: Shishkin, Sergey, et al.
Publicado: (2016)

Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer
por: Sannino, Giuseppina, et al.
Publicado: (2016)

Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system
por: Huth, Johannes, et al.
Publicado: (2010)

Par-3 for the cofilin course
por: LeBrasseur, Nicole
Publicado: (2006)

LIM kinases: cofilin and beyond
por: Prunier, Chloé, et al.
Publicado: (2017)

Role of Cofilin in Alzheimer’s Disease
por: Wang, Qiang, et al.
Publicado: (2020)

Stability of Signaling Pathways during Aging—A Boolean Network Approach
por: Schwab, Julian Daniel, et al.
Publicado: (2017)

Comprehensive Analysis of Cellular Galectin-3 Reveals No Consistent Oncogenic Function in Pancreatic Cancer Cells
por: Hann, Alexander, et al.
Publicado: (2011)

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
por: Davis, Richard C, et al.
Publicado: (2011)

Characterization of Sarcoptes scabiei cofilin gene and assessment of recombinant cofilin protein as an antigen in indirect-ELISA for diagnosis
por: Zheng, Yu, et al.
Publicado: (2016)

Cofilin-induced cooperative conformational changes of actin subunits revealed using cofilin-actin fusion protein
por: Umeki, Nobuhisa, et al.
Publicado: (2016)

VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays
por: Kestler, Hans A, et al.
Publicado: (2008)

Prognostic Significance of Cofilin Isoforms in Patients With Pancreatic Ductal Adenocarcinoma
por: Islam, Shajedul, et al.
Publicado: (2021)

Cofilin activity is a total coincidence
por: Sedwick, Caitlin
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_i4qokuk6omqpt5lgp87r98646c