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Update on New Aspects of the Renin-Angiotensin System in Hepatic Fibrosis and Portal Hypertension: Implications for Novel Therapeutic Options

There is considerable experimental evidence that the renin angiotensin system (RAS) plays a central role in both hepatic fibrogenesis and portal hypertension. Angiotensin converting enzyme (ACE), a key enzyme of the classical RAS, converts angiotensin I (Ang I) to angiotensin II (Ang II), which acts...

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Detalles Bibliográficos
Autores principales: Rajapaksha, Indu G., Gunarathne, Lakmie S., Angus, Peter W., Herath, Chandana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916881/
https://www.ncbi.nlm.nih.gov/pubmed/33670126
http://dx.doi.org/10.3390/jcm10040702