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Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions
Objective: To evaluate the safety and efficacy of the Phil liquid embolic agent in non-neurological embolization procedures. M&M: Thirty-five patients with a mean age of 62.5 years underwent percutaneous embolization using Phil for the treatment of visceral arterial bleedings in 20/35 patients (...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916888/ https://www.ncbi.nlm.nih.gov/pubmed/33670124 http://dx.doi.org/10.3390/jcm10040701 |
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author | Lucatelli, Pierleone Corona, Mario Teodoli, Leonardo Nardis, Piergiorgio Cannavale, Alessandro Rocco, Bianca Trobiani, Claudio Cipollari, Stefano Zilahi de Gyurgyokai, Simone Bezzi, Mario Catalano, Carlo |
author_facet | Lucatelli, Pierleone Corona, Mario Teodoli, Leonardo Nardis, Piergiorgio Cannavale, Alessandro Rocco, Bianca Trobiani, Claudio Cipollari, Stefano Zilahi de Gyurgyokai, Simone Bezzi, Mario Catalano, Carlo |
author_sort | Lucatelli, Pierleone |
collection | PubMed |
description | Objective: To evaluate the safety and efficacy of the Phil liquid embolic agent in non-neurological embolization procedures. M&M: Thirty-five patients with a mean age of 62.5 years underwent percutaneous embolization using Phil for the treatment of visceral arterial bleedings in 20/35 patients (including three gluteal, one bladder, two superior mesenteric, three epigastric, one deep femoral, five internal iliac, four intercostal, and one lingual arteries), splanchnic pseudoaneurysms in 11/35 patients (including three hepatic, five splenic, and three renal arteries), pancreatic bleeding metastasis in 1/35 patient, and gastric bleeding varices in 3/35 patients. Phil is composed of a non-adhesive copolymer dissolved in DMSO (Anhydrous Dimethyl Sulfoxide) with different viscosity. Procedures were performed slowly under continuous fluoroscopic guidance to avoid embolization of non-target vessels. Results: Clinical success was obtained with a single intervention in 34 cases (97.15%), while a repeated procedure was required in one case (2.85%). No technical complications nor non-target embolization occurred. A case of post-embolic syndrome was noted (2.85%) in one patient. DMSO administration-related pain was successfully controlled by medical therapy. Conclusion: Phil can be considered a safe and effective embolic agent for the treatment of non-neurologic bleeding. |
format | Online Article Text |
id | pubmed-7916888 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79168882021-03-01 Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions Lucatelli, Pierleone Corona, Mario Teodoli, Leonardo Nardis, Piergiorgio Cannavale, Alessandro Rocco, Bianca Trobiani, Claudio Cipollari, Stefano Zilahi de Gyurgyokai, Simone Bezzi, Mario Catalano, Carlo J Clin Med Article Objective: To evaluate the safety and efficacy of the Phil liquid embolic agent in non-neurological embolization procedures. M&M: Thirty-five patients with a mean age of 62.5 years underwent percutaneous embolization using Phil for the treatment of visceral arterial bleedings in 20/35 patients (including three gluteal, one bladder, two superior mesenteric, three epigastric, one deep femoral, five internal iliac, four intercostal, and one lingual arteries), splanchnic pseudoaneurysms in 11/35 patients (including three hepatic, five splenic, and three renal arteries), pancreatic bleeding metastasis in 1/35 patient, and gastric bleeding varices in 3/35 patients. Phil is composed of a non-adhesive copolymer dissolved in DMSO (Anhydrous Dimethyl Sulfoxide) with different viscosity. Procedures were performed slowly under continuous fluoroscopic guidance to avoid embolization of non-target vessels. Results: Clinical success was obtained with a single intervention in 34 cases (97.15%), while a repeated procedure was required in one case (2.85%). No technical complications nor non-target embolization occurred. A case of post-embolic syndrome was noted (2.85%) in one patient. DMSO administration-related pain was successfully controlled by medical therapy. Conclusion: Phil can be considered a safe and effective embolic agent for the treatment of non-neurologic bleeding. MDPI 2021-02-11 /pmc/articles/PMC7916888/ /pubmed/33670124 http://dx.doi.org/10.3390/jcm10040701 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lucatelli, Pierleone Corona, Mario Teodoli, Leonardo Nardis, Piergiorgio Cannavale, Alessandro Rocco, Bianca Trobiani, Claudio Cipollari, Stefano Zilahi de Gyurgyokai, Simone Bezzi, Mario Catalano, Carlo Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title | Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title_full | Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title_fullStr | Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title_full_unstemmed | Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title_short | Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions |
title_sort | use of phil embolic agent for bleeding in non-neurological interventions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916888/ https://www.ncbi.nlm.nih.gov/pubmed/33670124 http://dx.doi.org/10.3390/jcm10040701 |
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