Precision Surgery and Kidney Cancer: Knowledge of Genetic Alterations Influences Surgical Management

Renal cell carcinoma is a term that represents multiple different disease processes, each driven by different genetic alterations, with distinct histology, and biological potential which necessitates divergent management strategies. This review discusses the genetic alterations seen in several forms...

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Detalles Bibliográficos
Autores principales: Gomella, Patrick T., Linehan, W. Marston, Ball, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916897/
https://www.ncbi.nlm.nih.gov/pubmed/33670168
http://dx.doi.org/10.3390/genes12020261
Descripción
Sumario:Renal cell carcinoma is a term that represents multiple different disease processes, each driven by different genetic alterations, with distinct histology, and biological potential which necessitates divergent management strategies. This review discusses the genetic alterations seen in several forms of hereditary kidney cancer and how that knowledge can dictate when and how to intervene with a focus on the surgical management of these tumors.

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