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CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D

During normal pregnancy, the placental trophoblast secretes a variety of steroid hormones and participates in the regulation of maternal physiological functions and fetal development. The CYP11A1 gene encodes the cholesterol side-chain cleavage enzyme P450scc, which catalyzes the production of pregn...

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Detalles Bibliográficos
Autores principales:	Wang, Xiang, Li, Mengxue, Zhang, Xueguang, Li, Yaqian, He, Guolin, Dinnyés, Andras, Sun, Qun, Xu, Wenming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917044/ https://www.ncbi.nlm.nih.gov/pubmed/33659272 http://dx.doi.org/10.3389/fmolb.2020.608447

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