Cargando…

Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate

OBJECTIVE: The gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising pancreatitis and its reversal by butyrate supplementation....

Descripción completa

Detalles Bibliográficos
Autores principales:	van den Berg, Fons F, van Dalen, Demi, Hyoju, Sanjiv K, van Santvoort, Hjalmar C, Besselink, Marc G, Wiersinga, Willem Joost, Zaborina, Olga, Boermeester, Marja A, Alverdy, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Pancreas
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917160/ https://www.ncbi.nlm.nih.gov/pubmed/32873697 http://dx.doi.org/10.1136/gutjnl-2019-320430

Ejemplares similares

Prophylactic total pancreatectomy in individuals at high risk of pancreatic ductal adenocarcinoma (PROPAN): systematic review and shared decision-making programme using decision tables
por: Scholten, Lianne, et al.
Publicado: (2020)

Long-term yield of pancreatic cancer surveillance in high-risk individuals
por: Overbeek, Kasper A, et al.
Publicado: (2022)

The additive value of CA19.9 monitoring in a pancreatic cyst surveillance program
por: Levink, Iris J. M., et al.
Publicado: (2023)

Spatioregional assessment of the gut microbiota in experimental necrotizing pancreatitis
por: van den Berg, F F, et al.
Publicado: (2021)

Prevalence, features, and explanations of missed and misinterpreted pancreatic cancer on imaging: a matched case–control study
por: Hoogenboom, Sanne A., et al.
Publicado: (2022)

SARS-CoV-2 and the sympathetic immune response: Dampening inflammation with antihypertensive drugs (Clonidine and Propranolol)
por: Hyoju, Sanjiv K, et al.
Publicado: (2020)

Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease
por: Martens, Sandrina, et al.
Publicado: (2022)

Cost‐effectiveness of pancreas surveillance: The CDKN2A‐p16‐Leiden cohort
por: Ibrahim, Isaura S., et al.
Publicado: (2023)

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
por: Mahajan, Ujjwal M, et al.
Publicado: (2016)

Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model
por: Kumar, Sumit, et al.
Publicado: (2022)

Demonstration of intrahepatic accumulated microbubble on ultrasound represents the grade of hepatic fibrosis
por: Ishibashi, Hiroyuki, et al.
Publicado: (2011)

A faecal microbiota signature with high specificity for pancreatic cancer
por: Kartal, Ece, et al.
Publicado: (2022)

Mice Fed an Obesogenic Western Diet, Administered Antibiotics, and Subjected to a Sterile Surgical Procedure Develop Lethal Septicemia with Multidrug-Resistant Pathobionts
por: Hyoju, Sanjiv K., et al.
Publicado: (2019)

Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
por: Hackeng, Wenzel M, et al.
Publicado: (2022)

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis
por: Rosendahl, Jonas, et al.
Publicado: (2018)

Sustained Release of Phosphates From Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation in vitro
por: Nichols, Dylan, et al.
Publicado: (2019)

Impact of Tumor Grade on Prognosis in Pancreatic Cancer: Should We Include Grade in AJCC Staging?
por: Wasif, Nabil, et al.
Publicado: (2010)

Autoimmune pancreatitis results from loss of TGFβ signalling in S100A4-positive dendritic cells
por: Boomershine, C S, et al.
Publicado: (2009)

Combination 5-fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301)
por: Dahan, Laetitia, et al.
Publicado: (2010)

Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis
por: Huang, Wei, et al.
Publicado: (2014)

Targeting mTOR dependency in pancreatic cancer
por: Morran, Douglas C, et al.
Publicado: (2014)

Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis
por: Hart, Phil A, et al.
Publicado: (2013)

Opportunities of improvement in the management of pancreatic and periampullary tumors: Prospective evaluation of outcome from a multidisciplinary research program
por: Nordby, Tom, et al.
Publicado: (2013)

Time to progression of pancreatic ductal adenocarcinoma from low-to-high tumour stages
por: Yu, Jun, et al.
Publicado: (2015)

MRI with hyperpolarised [1-(13)C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model
por: Serrao, Eva M, et al.
Publicado: (2016)

The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
por: Cioffi, Michele, et al.
Publicado: (2015)

Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release
por: Huang, Wei, et al.
Publicado: (2017)

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
por: Mukherjee, Rajarshi, et al.
Publicado: (2016)

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer
por: Martinelli, Paola, et al.
Publicado: (2017)

Digital next-generation sequencing identifies low-abundance mutations in pancreatic juice samples collected from the duodenum of patients with pancreatic cancer and intraductal papillary mucinous neoplasms
por: Yu, Jun, et al.
Publicado: (2017)

Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
por: Zhang, Yaqing, et al.
Publicado: (2017)

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
por: Mayerle, Julia, et al.
Publicado: (2018)

Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility
por: Knudsen, Erik S, et al.
Publicado: (2018)

Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
por: Hessmann, E, et al.
Publicado: (2018)

Targeting both tumour-associated CXCR2(+) neutrophils and CCR2(+) macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
por: Nywening, Timothy M, et al.
Publicado: (2018)

Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
por: Goehrig, Delphine, et al.
Publicado: (2019)

Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma
por: Raj, Deepak, et al.
Publicado: (2019)

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer
por: Chou, Angela, et al.
Publicado: (2018)

Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia
por: Singhi, Aatur D, et al.
Publicado: (2018)

Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis
por: de la Iglesia-García, Daniel, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rdgg0rpunetm50vj63c9l6fsrd