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Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917299/ https://www.ncbi.nlm.nih.gov/pubmed/33680789 http://dx.doi.org/10.1016/j.eats.2020.10.038 |
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author | Cugat, Ramón Samitier, Gonzalo Vinagre, Gustavo Sava, Maria Alentorn-Geli, Eduard García-Balletbó, Montserrat Cuscó, Xavier Seijas, Roberto Barastegui, David Navarro, Jordi Laiz, Patricia |
author_facet | Cugat, Ramón Samitier, Gonzalo Vinagre, Gustavo Sava, Maria Alentorn-Geli, Eduard García-Balletbó, Montserrat Cuscó, Xavier Seijas, Roberto Barastegui, David Navarro, Jordi Laiz, Patricia |
author_sort | Cugat, Ramón |
collection | PubMed |
description | Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration procedures available to treat these injuries, such as bone marrow−stimulation techniques, osteoarticular auto/allograft transplants, and autologous chondrocyte implantation. Each of these techniques has its own limitations, which led researchers to explore new regenerative and repair techniques to produce normal hyaline cartilage. The purpose of this Technical Note is to describe in detail the particulated autologous chondral−platelet-rich plasma matrix implantation (PACI) technique that could be used as a single-stage cartilage restoration procedure for treatment of full-thickness cartilage and osteochondral defects. |
format | Online Article Text |
id | pubmed-7917299 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-79172992021-03-05 Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects Cugat, Ramón Samitier, Gonzalo Vinagre, Gustavo Sava, Maria Alentorn-Geli, Eduard García-Balletbó, Montserrat Cuscó, Xavier Seijas, Roberto Barastegui, David Navarro, Jordi Laiz, Patricia Arthrosc Tech Technical Note Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration procedures available to treat these injuries, such as bone marrow−stimulation techniques, osteoarticular auto/allograft transplants, and autologous chondrocyte implantation. Each of these techniques has its own limitations, which led researchers to explore new regenerative and repair techniques to produce normal hyaline cartilage. The purpose of this Technical Note is to describe in detail the particulated autologous chondral−platelet-rich plasma matrix implantation (PACI) technique that could be used as a single-stage cartilage restoration procedure for treatment of full-thickness cartilage and osteochondral defects. Elsevier 2021-01-16 /pmc/articles/PMC7917299/ /pubmed/33680789 http://dx.doi.org/10.1016/j.eats.2020.10.038 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Technical Note Cugat, Ramón Samitier, Gonzalo Vinagre, Gustavo Sava, Maria Alentorn-Geli, Eduard García-Balletbó, Montserrat Cuscó, Xavier Seijas, Roberto Barastegui, David Navarro, Jordi Laiz, Patricia Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title | Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title_full | Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title_fullStr | Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title_full_unstemmed | Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title_short | Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects |
title_sort | particulated autologous chondral−platelet-rich plasma matrix implantation (paci) for treatment of full-thickness cartilage osteochondral defects |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917299/ https://www.ncbi.nlm.nih.gov/pubmed/33680789 http://dx.doi.org/10.1016/j.eats.2020.10.038 |
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