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Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects

Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration...

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Autores principales: Cugat, Ramón, Samitier, Gonzalo, Vinagre, Gustavo, Sava, Maria, Alentorn-Geli, Eduard, García-Balletbó, Montserrat, Cuscó, Xavier, Seijas, Roberto, Barastegui, David, Navarro, Jordi, Laiz, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917299/
https://www.ncbi.nlm.nih.gov/pubmed/33680789
http://dx.doi.org/10.1016/j.eats.2020.10.038
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author Cugat, Ramón
Samitier, Gonzalo
Vinagre, Gustavo
Sava, Maria
Alentorn-Geli, Eduard
García-Balletbó, Montserrat
Cuscó, Xavier
Seijas, Roberto
Barastegui, David
Navarro, Jordi
Laiz, Patricia
author_facet Cugat, Ramón
Samitier, Gonzalo
Vinagre, Gustavo
Sava, Maria
Alentorn-Geli, Eduard
García-Balletbó, Montserrat
Cuscó, Xavier
Seijas, Roberto
Barastegui, David
Navarro, Jordi
Laiz, Patricia
author_sort Cugat, Ramón
collection PubMed
description Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration procedures available to treat these injuries, such as bone marrow−stimulation techniques, osteoarticular auto/allograft transplants, and autologous chondrocyte implantation. Each of these techniques has its own limitations, which led researchers to explore new regenerative and repair techniques to produce normal hyaline cartilage. The purpose of this Technical Note is to describe in detail the particulated autologous chondral−platelet-rich plasma matrix implantation (PACI) technique that could be used as a single-stage cartilage restoration procedure for treatment of full-thickness cartilage and osteochondral defects.
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spelling pubmed-79172992021-03-05 Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects Cugat, Ramón Samitier, Gonzalo Vinagre, Gustavo Sava, Maria Alentorn-Geli, Eduard García-Balletbó, Montserrat Cuscó, Xavier Seijas, Roberto Barastegui, David Navarro, Jordi Laiz, Patricia Arthrosc Tech Technical Note Articular hyaline cartilage injuries can occur as a result of either traumatic of progressive degeneration. When the articular cartilage in a joint is damaged, it can cause joint pain and dysfunction, predisposing patients for the development of early-onset osteoarthritis. There are many restoration procedures available to treat these injuries, such as bone marrow−stimulation techniques, osteoarticular auto/allograft transplants, and autologous chondrocyte implantation. Each of these techniques has its own limitations, which led researchers to explore new regenerative and repair techniques to produce normal hyaline cartilage. The purpose of this Technical Note is to describe in detail the particulated autologous chondral−platelet-rich plasma matrix implantation (PACI) technique that could be used as a single-stage cartilage restoration procedure for treatment of full-thickness cartilage and osteochondral defects. Elsevier 2021-01-16 /pmc/articles/PMC7917299/ /pubmed/33680789 http://dx.doi.org/10.1016/j.eats.2020.10.038 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Cugat, Ramón
Samitier, Gonzalo
Vinagre, Gustavo
Sava, Maria
Alentorn-Geli, Eduard
García-Balletbó, Montserrat
Cuscó, Xavier
Seijas, Roberto
Barastegui, David
Navarro, Jordi
Laiz, Patricia
Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title_full Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title_fullStr Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title_full_unstemmed Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title_short Particulated Autologous Chondral−Platelet-Rich Plasma Matrix Implantation (PACI) for Treatment of Full-Thickness Cartilage Osteochondral Defects
title_sort particulated autologous chondral−platelet-rich plasma matrix implantation (paci) for treatment of full-thickness cartilage osteochondral defects
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917299/
https://www.ncbi.nlm.nih.gov/pubmed/33680789
http://dx.doi.org/10.1016/j.eats.2020.10.038
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