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The Strategy of Conditionally Replicating Adenovirus-Mediated PreS2 Mini-Antibody Expression Has Dual Effects of Inhibiting HBV Infection and Preventing Hepatocellular Carcinoma
AIM: To investigate the inhibitory effect of hepatitis B virus (HBV) preS2 mini-antibody (mPreS2) against HBV infection, HBV-associated liver injury and HBV-associated hepatic carcinogenesis. METHODS: A recombinant adenovirus vector with the human survivin promoter and mPreS2 gene, Ad5SVP-mPreS2, wa...
Autores principales: | Ye, Ziheng, Zeng, Su, Xu, Peipei, Liu, Wenfei, Wang, Shoufei, Xia, Xiaotian, Su, Changqing, Guo, Minggao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917352/ https://www.ncbi.nlm.nih.gov/pubmed/33658851 http://dx.doi.org/10.2147/CMAR.S298331 |
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