Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium

Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regions https://bit.ly/3k6aAE8

Detalles Bibliográficos
Autores principales: Jacobs, Merel, Lahousse, Lies, Van Eeckhoutte, Hannelore P., Wijnant, Sara R.A., Delanghe, Joris R., Brusselle, Guy G., Bracke, Ken R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917434/
https://www.ncbi.nlm.nih.gov/pubmed/33889638
http://dx.doi.org/10.1183/23120541.00940-2020
Descripción
Sumario:Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regions https://bit.ly/3k6aAE8

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