Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium

Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regions https://bit.ly/3k6aAE8

Detalles Bibliográficos
Autores principales: Jacobs, Merel, Lahousse, Lies, Van Eeckhoutte, Hannelore P., Wijnant, Sara R.A., Delanghe, Joris R., Brusselle, Guy G., Bracke, Ken R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917434/
https://www.ncbi.nlm.nih.gov/pubmed/33889638
http://dx.doi.org/10.1183/23120541.00940-2020
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author Jacobs, Merel
Lahousse, Lies
Van Eeckhoutte, Hannelore P.
Wijnant, Sara R.A.
Delanghe, Joris R.
Brusselle, Guy G.
Bracke, Ken R.
author_facet Jacobs, Merel
Lahousse, Lies
Van Eeckhoutte, Hannelore P.
Wijnant, Sara R.A.
Delanghe, Joris R.
Brusselle, Guy G.
Bracke, Ken R.
author_sort Jacobs, Merel
collection PubMed
description Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regions https://bit.ly/3k6aAE8
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spelling pubmed-79174342021-03-01 Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium Jacobs, Merel Lahousse, Lies Van Eeckhoutte, Hannelore P. Wijnant, Sara R.A. Delanghe, Joris R. Brusselle, Guy G. Bracke, Ken R. ERJ Open Res Original Research Letters Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regions https://bit.ly/3k6aAE8 European Respiratory Society 2021-04-19 /pmc/articles/PMC7917434/ /pubmed/33889638 http://dx.doi.org/10.1183/23120541.00940-2020 Text en Copyright ©The authors 2021 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Original Research Letters
Jacobs, Merel
Lahousse, Lies
Van Eeckhoutte, Hannelore P.
Wijnant, Sara R.A.
Delanghe, Joris R.
Brusselle, Guy G.
Bracke, Ken R.
Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title_full Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title_fullStr Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title_full_unstemmed Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title_short Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
title_sort effect of ace1 polymorphism rs1799752 on protein levels of ace2, the sars-cov-2 entry receptor, in alveolar lung epithelium
topic Original Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917434/
https://www.ncbi.nlm.nih.gov/pubmed/33889638
http://dx.doi.org/10.1183/23120541.00940-2020
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