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Pyrrolidinedithiocarbamic Acid Ammonium Salt Inhibits Apoptosis and Phenotypic Transformation of Co-Culture of Myeloma Cells and Renal Tubular Epithelial Cells by Reducing the Secretion of Light Chain Protein

BACKGROUND: We investigate the effects of NFϰB inhibitor pyrrolidinedithiocarbamic acid ammonium salt (PDTC) on the viability, apoptosis and cell phenotype of HK-2 cells in the co-culture system of myeloma cells in renal tubular epithelial cells. METHODS: This study was performed in Qiqihar Medical...

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Detalles Bibliográficos
Autores principales: YU, Xiaoyan, BAO, Jie, CUI, Xinyu, DU, Fengxia, WANG, Yuefei, BI, Lili, SUN, Jun, LI, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917491/
https://www.ncbi.nlm.nih.gov/pubmed/33708728
http://dx.doi.org/10.18502/ijph.v49i11.4723