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Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in immunity is not. This is because while they are non‐neutralising, they somehow clear infection by coronavirus, influenza and LCMV in vivo. Here,...

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Detalles Bibliográficos
Autores principales: Caddy, Sarah L, Vaysburd, Marina, Papa, Guido, Wing, Mark, O’Connell, Kevin, Stoycheva, Diana, Foss, Stian, Terje Andersen, Jan, Oxenius, Annette, James, Leo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917548/
https://www.ncbi.nlm.nih.gov/pubmed/33258165
http://dx.doi.org/10.15252/embj.2020106228