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Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in immunity is not. This is because while they are non‐neutralising, they somehow clear infection by coronavirus, influenza and LCMV in vivo. Here,...
Autores principales: | Caddy, Sarah L, Vaysburd, Marina, Papa, Guido, Wing, Mark, O’Connell, Kevin, Stoycheva, Diana, Foss, Stian, Terje Andersen, Jan, Oxenius, Annette, James, Leo C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917548/ https://www.ncbi.nlm.nih.gov/pubmed/33258165 http://dx.doi.org/10.15252/embj.2020106228 |
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